Business Details
25 Years
experience
La Jolla Bioengineering Institute - Leading Nonprofit Research in Cell Membrane Mechanics
Established in 2001, La Jolla Bioengineering Institute serves as a dedicated research hub for investigators exploring diseases rooted in cell membrane mechanics. Our work focuses on arteriosclerosis, osteoporosis, Alzheimer's, and malaria pathogenesis, combining fluid and solid mechanics with molecular biology to advance clinical understanding. As a California 501(c)3 organization, we maintain 10,500 square feet of laboratory space and hold critical compliance certifications including Federal Welfare Assurance and Animal Welfare Assurance.Our interdisciplinary approach has produced seminal contributions to cerebral malaria research, identifying therapeutic strategies that improve survival rates. Affiliated with BIOCOM and the Association of Independent Research Institutes, we uphold rigorous scientific standards through our Institutional Review Board and Board of Trustees oversight.
Services
Cell Membrane Mechanics
Malarial Pathogenesis
Microcirculatory Physiology
Nitric Oxide Biology
Blood Substitute Development
Details
- Year established: 2001
Highlights and features
- We have over 20 years of focused research on cell membrane mechanics.
- Our interdisciplinary approach combines fluid mechanics and molecular biology.
- Our work provides insights with direct clinical relevance.
- We are pioneers in malaria cerebrovascular pathogenesis research.
- Affiliated with leading research organizations like BIOCOM.
Services
Cell Membrane Mechanics
Our research examines how mechanical forces affect blood vessels, bone, and muscle at the cellular level. This work provides critical insights into diseases like arteriosclerosis and osteoporosis. Our findings contribute directly to developing novel therapeutic approaches for these conditions.
Malarial Pathogenesis
We investigate microcirculatory complications in cerebral malaria using in vivo models and brain intravital microscopy. Our work identifies therapeutic targets to improve survival rates when combined with antimalarial drugs. This research has produced groundbreaking discoveries in vascular pathology treatment.
Microcirculatory Physiology
Our team studies microcirculatory dynamics to understand how blood flow affects tissue health. This research informs treatments for conditions involving impaired circulation. Advanced imaging techniques enable real-time observation of these critical physiological processes.
People
John A. Frangos
President & CEO/Scientific Director
Dr. Frangos leads our research initiatives with expertise in bioengineering and molecular biology. He has received multiple awards including the IET Medal in Bioengineering and NIH funding. His work focuses on mechanochemical signal transduction in vascular cells.
Nathaniel dela Paz
Assistant Professor
Dr. dela Paz contributes to our malaria research program with specialized knowledge in microcirculatory pathogenesis. His work advances understanding of vascular complications in infectious diseases. He collaborates on developing adjunctive therapies for cerebral malaria.
Questions
What research areas does La Jolla Bioengineering Institute focus on?
We specialize in cell membrane mechanics, cerebral malaria pathogenesis, microcirculatory physiology, and nitric oxide biology research.
How can I collaborate with your research team?
Contact us at (858) 456-7505 to discuss potential collaborations or facility access opportunities.
Is your institute affiliated with academic institutions?
Our scientists maintain academic connections through publications and professional organizations like BMES.
How is your malaria research applied clinically?
We identify therapeutic targets for cerebral malaria that improve survival when combined with standard treatments.
